. 2018 Oct 3;8:14783. doi: 10.1038/s41598-018-32847-8

Table 1.

Differential metabolites of glioma specimens detected by UPLC/QTOF-MS.

No	Metabolites Common name	Retention Time	Molecular Mass	Formula	Trend (Tvs C)	VIP	Class
1	pAp/ 3′-Phosphoadenylate	9.55	427.2011	C₁₀H₁₅N₅O₁₀P₂	↑^**	7.12	Purine Nucleotides
2	Appr > p/ ADP-ribose 1′′-2′′ cyclic phosphate	2.19	621.2804	C₁₅H₂₂N₅O₁₆P₃	↑^**	4.65	Purine Nucleotides
3	2-Hexaprenyl-6-methoxyphenol	2.11	532.8393	C₃₇H₅₆O₂	↑ ^**	5.25	Prenol lipids
4	DG(33:3)/ DG(15:0/18:3(9Z,12Z,15Z)/0:0)	20.80	576.8904	C₃₆H₆₄O₅	↑^**	8.03	Glycerolipids
5	CE(15:0)/ 15:0 cholesterol ester	6.01	611.0358	C₄₂H₇₄O₂	↑^**	7.32	Cholesterol ester
6	PC(36:1)/ PC(18:1(11Z)/18:0)	14.88	788.1293	C₄₄H₈₆NO₈P	↓^**	6.06	Glycerophosphatidylcholine
7	PC(36:3)/ PC(22:2(13Z,16Z)/14:1(9Z))	18.04	784.0975	C₄₄H₈₂NO₈P	↑^**	7.01	Glycerophosphatidylcholine
8	PC(38:6)/ PC(20:5(5Z,8Z,11Z,14Z,17Z)/P-18:1(11Z))	16.78	790.1037	C₄₆H₈₀NO₇P	↑^**	7.59	Glycerophosphatidylcholine
9	PC(38:4)/ PC(P-18:0/20:4(5Z,8Z,11Z,14Z))	20.39	794.1354	C₄₆H₈₄NO₇P	↑^**	8.31	Glycerophosphatidylcholine
10	LysoPC(O-18:0)	15.44	509.6997	C₂₆H₅₆NO₆P	↑^**	8.74	Lyso-glycerophosphatidylchoine
11	LysoPE(18:3)/ LysoPE(18:3(6Z,9Z,12Z)/0:0)	10.52	475.5558	C₂₃H₄₂NO₇P	↑^**	7.87	Lyso-glycerophosphatidylethanolamine
12	LysoPE(20:3)/ LysoPE(20:3(8Z,11Z,14Z)/0:0)	12.85	503.6090	C₂₅H₄₆NO₇P	↑^**	7.19	Lyso-glycerophosphatidylethanolamine
13	LysoPE(18:0)/ LysoPE(0:0/18:0)	13.94	481.6035	C₂₃H₄₈NO₇P	↑^**	6.95	Lyso-glycerophosphatidylethanolamine
14	Ceramide(d18:1/16:0)/C16 Cer	16.36	537.9007	C₃₄H₆₇NO₃	↑^**	6.68	Sphingolipids
15	Sphingomyelin SM(d18:0/12:0)/C12 sphingomyelin	16.86	650.9536	C₃₅H₇₅N₂O₆P	↑^**	7.56	Sphingomyelin(with phosphocholine)

Foot notation: 1. (T VS C) means tumor vs control. 2. VIP: variable importance in the project. **p ≤ 0.01.