Table 1.

The CLL-International Prognostic Index³⁰

Prognostic factor	Points
Del17p on FISH or TP53 mutation	4
Unmutated IGHV genes	2
Serum β2 microglobulin >3.5 mg/L	2
Rai stage I–IV	1
Age >65 years	1

Cumulative CLL-IPI score	Risk category	5-year TFSa
0–1	Low risk	78%
2–3	Intermediate risk	54%
4–6	High risk	32%
7–10	Very high risk	0%

FISH fluorescence in situ hybridization, IGHV immunoglobulin heavy chain gene, TFS treatment-free survival

^aFor the Mayo validation cohort