Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 3;8:14728. doi: 10.1038/s41598-018-33016-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Cationic peptide 6K-F17 potentiates tobramycin activity against P. aeruginosa biofilms. 30-hour slide chamber P. aeruginosa PAO1 biofilms were grown with tobramycin alone in increasing concentrations, or with a fixed concentration (10 µg/mL) of 6K-F17 + increasing concentrations of tobramycin for 16 hours prior to confocal imaging and analysis of biovolume. (a) Total biofilm biovolume expressed as percentage of untreated controls. The mean of n = 12 images from N = 4 biological experiments is plotted. Comparison of means between conditions was performed using a Kruskal-Wallis test with a Dunn’s multiple comparison post-test. (b) ATP cell viability assay of PAO1 biofilms exposed to increasing concentrations of tobramycin alone fixed concentration (10 µg/mL) of 6K-F17 + increasing concentrations of tobramycin for 16 hours. PAO1 was grown in 96-well microtiter plates and ATP assays were performed as described in the methods. The mean of n = 4 experiments is plotted. Comparison of means between conditions was performed using a Mann-Whitney U test, **p < 0.01. Error is reported as standard error of the mean.