Fig. 5. TRPC6 knockout attenuates oxidative stress-induced cell apoptosis.

Primary PTC from WT and TRPC6^-/- mice were divided into different groups and treated with H₂O₂ (0.5 mM) for 12 h. a Representative western blot images and the relative quantification of cleaved caspase-3 (CC3). Data are expressed as mean ± SEM, n = 3; *P < 0.05. b Representative TUNEL staining of PTC in each group. Scale Bar = 50 μm. Bar graph is showing the quantification of TUNEL-positive cells. Data are expressed as mean ± SEM, n = 6; *P < 0.05