Fig. 3.

Estimating the usefulness of the prior network for the task of inferring sex-specific GRNs for Drosophila. The relevance of a prior network is estimated by PriorBoost scores where negative score indicate that the prior might be misleading. As an additional test we used PPI score which evaluates the topology of a network independently of its relation to expression data. When the PriorBoost scores are positive, PPI scores of NetREX are higher than GENIE3. For each box in the boxplot, the central mark (black line) indicates the median, and the bottom and top edges of the box indicate the 25th and 75th percentiles, respectively