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. 2018 Sep 27;6:123. doi: 10.3389/fcell.2018.00123

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Copyright © 2018 Tunster, Boqué-Sastre, McNamara, Hunter, Creeth and John.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Summary of gene expression data in relation to placental lineages. Peg3 is required for the expansion of both the glycogen cell and spongiotrophoblast lineages. Genes indicated in red are significantly reduced in expression in male Peg3 KO placenta. Genes indicated in green are significantly elevated in female Peg3 KO placenta. ICM, inner cell mass; TE, trophectoderm; TGCs, trophoblast giant cells; ExM, extraembryonic mesoderm; ExE, extraembryonic ectoderm; EPC, ectoplacental cone; SynT, syncitiotrophoblast.