FIGURE 3.

Aloe polysaccharides interferes with viral adsorption to MDCK cells. MDCK monolayers were infected with MOI = 1 of PR8 virus in the absence (A) or presence (B) of APS treatment (40 μg/mL). At 4 h post-infection, the cells were centrifuged and fixed to prepare ultrathin sections, and the virions in cells were imaged via TEM (30000×). The virions on the cell membrane surface and in the endosomes were denoted by black arrowheads. Te purified PR8 virus (C) and the mixture of virus and APS (D) were imaged via TEM after negative staining (60000×). The virions were denoted by black arrowheads.