Skip to main content
. 2018 Sep 27;9:2091. doi: 10.3389/fimmu.2018.02091

Figure 2.

Figure 2

PPI ameliorated the inflammatory cytokines production of BMMs stimulated by LPS/IFN-γ. (A–D) IL-1β, IL-6, TNF-α, and NOS2 mRNA expression of BMMs stimulated with LPS (1 μg/ml) /IFN-γ (100 ng/ml) for 6 h in the presence of PPI (0, 0.5, or 1 μM) pretreated for 3 h. Representative data of at least 3 mice. Data represent mean ± SEM. NS, P > 0.05, *P < 0.05, One-way analysis of variance (ANOVA). (E–H) ELISA in the supernatants of BMMs stimulated with LPS/ IFN-γ for 6 h (IL-1β, IL-6, and TNF-α) and 24 h (NO) in the presence of PPI (0.25, 0.5, or 1 μM) pretreated for 3 h. Data represents mean ± SEM of four pooled experiments. NS, P > 0.05, *P < 0.05, One-way ANOVA.