Table 1.
Variable | Sham (n = 10) | MI (n = 7) | MI+LSH (n = 8) | MI+HSH (n = 8) |
---|---|---|---|---|
Rat characteristics | ||||
Body weight, g | 297.2 ± 14.21 | 291.28 ± 18.48 | 306.62 ± 10.42 | 301 ± 16.14 |
Heart weight, mg | 837.1 ± 70.2 | 1292.86 ± 62.11* | 1134.75 ± 44.46∗# | 1030.5 ± 73.96∗#∧ |
Heart weight/body weight, mg/g | 2.83 ± 0.33 | 4.45 ± 0.21* | 3.71 ± 0.22∗# | 3.44 ± 0.36∗#∧ |
Left ventricular weight, mg | 578.9 ± 40.54 | 917.14 ± 40.48* | 846.25 ± 26.34∗# | 730.5 ± 39.53∗#∧ |
Left ventricular weight/body weight, mg/g | 1.95 ± 0.18 | 3.16 ± 0.23* | 2.76 ± 0.14∗# | 2.43 ± 0.09∗#∧ |
Cardiac function | ||||
Heart rate, bpm | 390.8 ± 10.65 | 466.86 + 20.01∗ | 430.12 ± 9.43∗# | 412 ± 12.2∗#∧ |
LVEDd, mm | 5.15 ± 0.55 | 7.94 ± 0.29* | 7.50 ± 0.26∗# | 7.10 ± 0.24∗#∧ |
LVESd, mm | 2.81 ± 0.49 | 6.58 ± 0.19* | 5.99 ± 0.28∗# | 5.40 ± 0.39∗#∧ |
LVEF, % | 83.52 ± 5.03 | 42.83 ± 5.02* | 48.90 ± 4.37∗# | 55.70 + 6.90∗#∧ |
Sham, Sham group; MI, myocardial infarction group; MI+LSH, myocardial infarction+low dose Sodium Houttuyfonate group; MI+HSH, myocardial infarction+high dose Sodium Houttuyfonate group; ∗compared with Sham group, p < 0.05; #compared with MI group, p < 0.05; ∧compared with MI+LSH group, p < 0.05.