(A) The probability distribution functions (PDFs) of the open times for different scaled times α. When a specific α is listed, all events with closed times t with 0.9ατ3 ≤ t < 1.1ατ3 are chosen and the distribution of the subsequent open times is shown. Top row, high luminal Ca2+; bottom row, low. (B) Metrics of the smoothed histograms described in the Supporting Materials and Methods, specifically the standard deviations (top row) and means (bottom row). (C) Open-time PDFs for all recorded openings are shown. (D) Distribution means are shown like in (B), but for closed-time distributions rather than open-time distributions. (E) PDFs are shown as in (A), but for closed-time distributions. To see this figure in color, go online.