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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Neuropharmacology. 2018 Aug 28;141:192–200. doi: 10.1016/j.neuropharm.2018.08.019

Figure 2. Local nicotine infusion into the vHPC and PL result in contextual fear extinction deficits.

Figure 2.

A. Local nicotine infusion into the dHPC did not affect normalized %freezing scores across 4 extinctions sessions (n=7 per group). B. vHPC local nicotine infusions disrupted contextual fear extinction (n=7 per group). C. IL nicotine infusions had no effect on contextual fear extinction (n=4–6 per group). D. Local nicotine infusions into the PL also resulted in impaired extinction of contextual fear. (n=5 per group). Right panels show placement of guide cannulas. Error bars show standard error of the mean. *p<0.05; **p<0.01; ***p<0.001 compared to Saline controls.