Table 1.
Characteristics of 1,011 stage III colon cancer patients, by post-diagnostic intake of animal and vegetable fat.
| Quartile of Animal Fat | Quartile of Vegetable Fat | |||||
|---|---|---|---|---|---|---|
| 1 | 4 | 1 | 4 | |||
| N | 252 | 253 | 252 | 253 | ||
|
Characteristic, median (IQR) or % |
p- value |
p-value | ||||
| Male | 56 | 60 | 0.26 | 54 | 54 | 0.20 |
| Age, years | 62 (54, 70) | 57 (51, 67) | 0.01 | 60 (51, 69) | 62 (54, 69) | 0.03 |
| Race | 0.14 | 0.41 | ||||
| White | 89 | 86 | 86 | 90 | ||
| Black | 5 | 10 | 8 | 6 | ||
| Other | 6 | 4 | 6 | 4 | ||
| Performance status | 0.29 | 0.40 | ||||
| Fully active | 76 | 68 | 72 | 73 | ||
| Restricted in strenuous activity |
21 | 30 | 27 | 26 | ||
| Unknown | 3 | 2 | 1 | 1 | ||
| Bowel wall invasion | 0.89 | 0.87 | ||||
| T1-T2 | 15 | 14 | 12 | 13 | ||
| T3-T4 | 77 | 80 | 83 | 79 | ||
| Unknown | 8 | 6 | 5 | 8 | ||
| Positive lymph nodes | 0.65 | 0.26 | ||||
| 1–3 (N1) | 62 | 64 | 67 | 64 | ||
| ≥4 (N2) | 35 | 34 | 32 | 35 | ||
| Unknown | 3 | 2 | 1 | 1 | ||
| Clinical bowel abnormality | ||||||
| Perforation | 3 | 6 | 0.34 | 3 | 7 | 0.10 |
| Obstruction | 23 | 25 | 0.31 | 22 | 23 | 0.32 |
| Grade of differentiation | 0.88 | 0.26 | ||||
| Well | 4 | 6 | 7 | 6 | ||
| Moderate | 71 | 68 | 68 | 72 | ||
| Poor | 22 | 24 | 25 | 21 | ||
| Unknown | 3 | 2 | 1 | 1 | ||
| Treatment arm | 0.88 | 0.006 | ||||
| Fluorouracil + leucovorin |
51 | 51 | 56 | 57 | ||
| Irinotecan, fluorouracil, leucovorin |
49 | 49 | 44 | 43 | ||
| Smoking status | 0.33 | 0.94 | ||||
| Current | 6 | 13 | 12 | 10 | ||
| Past | 48 | 44 | 44 | 43 | ||
| Never | 45 | 42 | 44 | 45 | ||
| Unknown | 1 | 1 | 1 | 1 | ||
| Aspirin user | 9 | 8 | 0.72 | 7 | 7 | 0.73 |
| BMI, kg/m2 | 26.7 (23.8, 29.9) | 29.3 (25.0, 33.9) | <0.001 | 27.5 (24.1, 32.1) | 28.3 (24.7, 31.8) | 0.26 |
| Physical activity, MET h/wk |
7.7 (2.2, 23.2) | 5.9 (1.7, 16.7) | 0.09 | 7.4 (2.7, 18.1) | 5.7 (1.6, 16.5) | 0.11 |
| Energy, kcal/d | 1848 (1532, 2327) |
1915 (1502, 2334) |
0.59 | 1866 (1553, 2336) |
1794 (1457, 2309) |
0.29 |
| Animal fat, g/d | 27 (23, 29) | 50 (47, 55) | <0.001 | 39 (31, 48) | 35 (29, 42) | <0.001 |
| Vegetable fat, g/d | 34 (28, 42) | 30 (24, 36) | <0.001 | 23 (20, 25) | 46 (42, 52) | <0.001 |
| Carbohydrate, g/d | 284 (266, 307) | 225 (205, 241) | <0.001 | 267 (240, 293) | 237 (213, 260) | <0.001 |
| Protein, g/d | 76 (66, 87) | 89 (81, 100) | <0.001 | 89 (76, 101) | 76 (68, 86) | <0.001 |
Abbreviations: BMI, body mass index; MET, metabolic equivalent task.
1
P-value calculated using chi-square tests for categorical measures and Kruskal Wallis tests for continuous measures.