Figure 2.

Experiments of intercellular mechanical interaction. (a) Two GFP-actin cells (gray) embedded in fluorescently labeled fibrin gel (white) are shown. The images show the overlay of cells and fibrin matrix (left) and the cells only (right). (b) The mean orientation of the fibers in the intercellular region of the ECM and far away from the cells is shown; 0° is defined as the line connecting the centers of the two cells. (c) The fluorescence intensity of the matrix as measured both within the intercellular region of the matrix and far away from the cells is shown. For a full-color version of this figure, the reader is referred to the online version of the article.