Table 3.
Comparison of HT and GD patients according to ANA or RF positivity
| Positive ANA | Negative ANA | p value | Positive RF | Negative RF | p value | |
|---|---|---|---|---|---|---|
|
Hashimoto thyroiditis (n = 70) Number |
14 | 56 | 4 | 66 | ||
| Age, years, mean ± SD | 48.71±10.63 | 45.95±14.69 | 0.51 | 52.25±7.63 | 46.15±14.20 | 0.39 |
| Caucasian ethnic background, n (%) | 10 (71.42) | 50 (89.28) | 0.10 | 4 (100.00) | 56 (84.84) | 1.00 |
| Smokers, n (%) | 5 (35.71) | 16 (28.57) | 0.74 | 1 (25.00) | 20 (30.30) | 1.00 |
| Arthralgias, n (%) | 8 (57.14) | 36 (64.28) | 0.62 | 4 (100) | 40 (60.6) | 0.56 |
| Daily T4 dose, µg/kg, mean ± SD | 1.71±0.76 | 1.55±0.58 | 0.41 | 1.32±0.27 | 1.60±0.63 | 0.39 |
|
Graves disease (n = 84) Number |
13 | 71 | 8 | 76 | ||
| Age, years, mean ± SD | 50.00±14.91 | 43.41±14.20 | 0.13 | 57.63±17.19 | 43.04±13.49 | 0.005 |
| Caucasian ethnic background, n (%) | 10 (76.92) | 48 (67.60) | 0.74 | 6 (75) | 52 (68.42) | 1.00 |
| Smokers, n (%) | 5 (38.46) | 20 (28.16) | 0.45 | 5 (62.5) | 20 (26.31) | 0.04* |
| Arthralgias, n (%) | 7 (53.84) | 43 (60.56) | 0.65 | 5 (62.50) | 45 (59.21) | 1.00 |
| Tapazole and propylthiouracil users, n (%) | 3 (23.07) | 12 (16.90) | 0.69 | 2 (25) | 13 (17.10) | 0.10 |
*
OR 4.66; 95% CI 1.02–21.34.
HT, Hashimoto thyroiditis; GD, Graves' disease; ANA, antinuclear antibody; RF, rheumatoid factor.