Table 2.
Baseline characteristics of the diabetic patients in the study population
| Normal renal function (n = 627) | Mild CKD (n = 887) | Moderate CKD (n = 111) | p | |
|---|---|---|---|---|
| Age, years | 56.3±10.3 | 60.6±10.2 | 69.1±8.6 | <0.001 |
| Male | 451 (71.9) | 637 (71.8) | 56 (50.5) | <0.001 |
| Body mass index | 24.7±3.6 | 25.0±3.3 | 25.0±2.9 | 0.145 |
| SBP, mm Hg | 124.8±14.6 | 125.4±13.9 | 130.0±16.3 | 0.003 |
| DBP, mm Hg | 76.1±10.4 | 75.4±10.0 | 75.1±9.1 | 0.355 |
| Hypertension | 239 (40.1) | 404 (47.8) | 87 (79.1) | <0.001 |
| Smoking | 167 (42.4) | 195 (37.1) | 19 (22.4) | 0.002 |
| Dyslipidemia | 288 (45.9) | 460 (51.9) | 72 (64.9) | 0.001 |
| Hemoglobin, mg/dL | 14.4±1.5 | 14.3±1.7 | 13.0±1.7 | <0.001 |
| eGFR | 103.6±13.0 | 78.0±7.7 | 52.5±7.1 | <0.001 |
| Total cholesterol, mL/dL | 183.1±39.4 | 185.3±40.2 | 169.5±43.2 | 0.001 |
| Triglyceride, mL/dL | 139.1±107.6 | 134.3±88.3 | 139.1±66.8 | 0.606 |
| HDL cholesterol, mL/dL | 49.1±12.2 | 48.2±11.5 | 46.2±11.4 | 0.042 |
| LDL cholesterol, mL/dL | 107.7±34.1 | 112.6±35.7 | 100.7±40.4 | 0.003 |
| HbA1C, % | 9.1±3.7 | 9.5±4.0 | 8.7±3.5 | 0.037 |
| hs-CRP, mg/L | 3.4±1.2 | 3.6±1.4 | 6.5±3.4 | 0.287 |
Data are given as the mean ± SD or n (%). CKD, chronic kidney disease; SBP, systolic blood pressure; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein; HbA1C, glycosylated hemoglobin; hs-CRP, high-sensitivity C-reactive protein.