Table 2.
Clinicopathologic features of 76 patients with gallbladder cancer enrolled in this study.
| Observed clinicopathologic features | Count (Percentage) |
|---|---|
| Comorbidities and risk factors | n (%) |
| Diabetes | 38 (50) |
| Hypertension | 38 (50) |
| Smoking | 12 (16) |
| Gallstones | 57 (75) |
| Size of gallstones: | |
| Multiple, ≤1 cm | 43 (57.9) |
| Between 1 and 2 cm | 10 (13.2) |
| > 2 cm | 6 (7.9) |
| Presenting symptom | n (%) |
| Obstructive jaundice | 1 (1) |
| Right upper quadrant pain | 64 (84) |
| Epigastric pain | 4 (5) |
| Right upper quadrant and epigastric pain | 2 (3) |
| Vomiting and epigastric pain | 2 (3) |
| Painless obstructive jaundice | 2 (3) |
| Anorexia with weight loss and constipation | 1 (1) |
| Primary clinical diagnosis | n (%) |
| Biliary colic | 33 (43.4) |
| Acute cholecystitis | 24 (31.6) |
| Biliary pancreatitis | 7 (9.2) |
| Painless obstructive jaundice secondary to malignancy | 1 (1.3) |
| Chronic calcular cholecystitis | 10 (13.2) |
| Irritable bowel syndrome | 1 (1.3) |
| Imaging findings | n (%) |
| Metastatic GBC | 38 (50) |
| Gallbladder mass | 8 (10.5) |
| Gallbladder mucocele | 1 (1.3) |
| Adenomyomatosis of gallbladder | 1 (1.3) |
| No incidental findings (gallstones) | 27 (36.8) |
| Intraoperative diagnosis | n (%) |
| Gallstones | 24 (31.6) |
| Gallstones with polyp | 3 (3.9) |
| Metastatic GBC | 7 (9.2) |
| GBC | 9 (11.8) |
| Adenomyomatosis of gallbladder | 1 (1.3) |
| None | 32 (42.1) |
| Procedure of staging | n (%) |
| Surgical | 30 (39) |
| Clinical | 46 (61) |
| Pathological staging post-cholecystectomy | n (%) |
| Stage I | 3 (3.9) |
| Stage II | 13 (17.1) |
| Stage IIB | 1 (1.3) |
| Stage IIIB | 2 (2.6) |
| Stage IVB | 57 (75) |
| GBC type | n (%) |
| Adenocarcinoma (NOS) | 57 (75) |
| Papillary adenocarcinoma | 7 (9.2) |
| Mucinous adenocarcinoma | 3 (3.9) |
| Carcinosarcoma | 3 (3.9) |
| Papillary carcinoma | 1 (1.3) |
| Squamous cell carcinoma | 1 (1.3) |
| Neuroendocrine carcinoma | 1 (1.3) |
| Sarcomatoid carcinoma | 1 (1.3) |
| Adenosquamous carcinoma | 1 (1.3) |
| Poorly differentiated carcinoma | 1 (1.3) |
| Resectability | n (%) |
| Yes | 31 (40.8) |
| No | 47 (61.8) |
| Surgical resection attempted | n (%) |
| Yes | 31 (40.8) |
| Successful | 21 (67.7) |
| Unsuccessful | 10 (32.3) |
| No | 45 (59.2) |
| Lymphadenectomy | n (%) |
| Yes | 24 (31.6) |
| No | 52 (68.4) |
| Excision site | n (%) |
| Bile duct | 20 (26.3) |
| Port site | 13 (17.1) |
| Survival to the end of study period | n (%) |
| No | 44 (57.9) |
| Yes | 20 (26.3) |
| Lost follow up (censored) | 12 (15.8) |
| Recurrence | n (%) |
| Yes | 8 (10.5) |
| No | 14 (18.4) |
| Unresectable disease or lost follow up | 54 (71.0) |
| Disease stage upon recurrence | n (%) |
| Stage II | 4 (50.0) |
| Stage IVB | 4 (50.0) |