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Concentrations of parent drug and metabolites in plasma and PBMCs. Median (minimum-maximum) concentration of TFV, FTC, TAF, TFVdp, and FTCtp in plasma (left) and PBMCs (right) after a single dose of 300 mg TDF, 200 mg FTC, or 25 mg TAF. All data are represented for TDF and FTC; TAF data are represented through 48 hours of study (total study, 14 days; 48-hour data point imputed).
