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. 2018 Nov;367(2):222–233. doi: 10.1124/jpet.118.250902

TABLE 1.

Pharmacokinetic parameters for plasma and brain distribution of SRI-31142 after administration of 10 mg/kg, i.p.

Parameter Brain Plasma
Tmax 10 min 10 min
Cmax 35.2 ng/ml (77.1 nM) 1125 ng/ml (2.5 µM)
t1/2 Not determined 4.4 h
AUC 18.2 h/ng per milliliter 880 h/ng per milliliter

AUC, area under the curve; t1/2, half-life.