Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Rodent models of perturbed hepatic triglyceride synthesis. Various genetic loss-of-function and gain-of function rodent models have been generated to test the role of diacylglycerol (DAG) in lipid-induced hepatic insulin resistance. These models are broadly consistent with the DAG/protein kinase C (PKC)ε hypothesis of lipid-induced hepatic insulin resistance. TAG, triacylglycerol; HFD, high-fat diet, KO, knockout. See text for details and references.
