Table 1.

Characteristics of eligible enrolled studies.

Gene	Polymorphism	First author	Year	Ethnicity	Source of Control	Cancer Type	Case			Control
							WW	WM	MM	WW	WM	MM
IL18	rs1946518	Teixeira et al.35	2013	mixed	P-B	HCC	38	56	18	85	105	12
	rs1946518	Lau et al.27	2016	Asian	H-B	HCC	88	167	87	148	276	135
	rs1946518	Bao et al.25	2015	Asian	P-B	HCC	37	73	43	41	76	48
	rs1946518	Migita et al.29	2009	Asian	P-B	HCC	13	26	8	20	30	13
	rs1946518	Chen et al.26	2012	Asian	P-B	HCC	47	126	55	83	156	61
	rs1946518	Karra et al.28	2015	African	P-B	HCC	70	152	49	102	144	34
	rs1946518	Zhang et al.32	2016	Asian	P-B	HCC	32	55	22	23	66	38
	rs187238	Kim et al.31	2009	Asian	H-B	HCC	37	17	2	434	122	2
	rs187238	Teixeira et al.35	2013	mixed	P-B	HCC	57	48	7	100	84	18
	rs187238	Lau et al. 27	2016	Asian	H-B	HCC	266	73	3	476	78	5
	rs187238	Bao et al. 25	2015	Asian	P-B	HCC	122	28	3	106	54	5
	rs187238	Migita et al. 29	2009	Asian	P-B	HCC	43	3	1	52	10	1
	rs187238	Chen et al. 26	2012	Asian	P-B	HCC	159	59	10	173	115	12
	rs187238	Karra et al. 28	2015	African	P-B	HCC	123	134	14	159	108	13
	rs187238	Zhang et al. 32	2016	Asian	P-B	HCC	82	25	2	99	24	4
IFN-γ	rs2430561	Teixeira et al.30	2013	Caucasian	P-B	HCC	40	50	21	79	82	41
	rs2430561	Kim et al.35	2013	Asian	H-B	HCC	133	31	6	131	38	2
	rs2430561	Migita et al.36	2005	Asian	H-B	HCC	41	7	0	157	31	0
	rs2430561	Ben-Ari et al.39	2003	Caucasian	P-B	HCC	3	7	0	18	24	6
	rs2430561	Nieters et al.37	2005	Asian	H-B	HCC	155	94		164	86
	rs2430561	Saxena et al.38	2014	Asian	P-B	HCC	15	28	16	52	77	17
	rs2430561	Bouzgarrou et al.34	2009	African	P-B	HCC	17	21	20	33	47	23
	rs2430561	Bahgat et al.33	2015	Egyptian	P-B	HCC	10	24	16	6	15	4
IL12A	rs568408	Elsayed et al.40	2016	Egyptian	P-B	HCC	42	26	10	84	7	1
	rs568408	Tan et al.42	2015	Asian	P-B	HCC	313	76	6	511	161	14
	rs568408	Liu et al.41	2011	Asian	P-B	HCC	504	277	21	631	220	10
IL12B	rs3212227	Saxena et al.38	2014	Asian	P-B	HCC	19	31	9	63	71	14
	rs3212227	Elsayed et al.40	2016	Egyptian	P-B	HCC	41	22	15	38	40	14
	rs3212227	Nieters et al.37	2005	Asian	H-B	HCC	56	193		72	178
	rs3212227	Tan et al.42	2015	Asian	P-B	HCC	104	201	90	200	347	139
	rs3212227	Ognjanovic et al.43	2009	mixed	P-B	HCC	57	60		128	95
	rs3212227	Liu et al.41	2011	Asian	P-B	HCC	249	422	160	272	414	158
	rs3212227	Yang et al.44	2011	Asian	H-B	HCC	156	309	143	195	302	115
STAT4	rs7574865	Chanthra et al.45	2015	Asian	P-B	HCC	19	86	87	28	100	62
	rs7574865	Chen et al.21	2013	Asian	H-B	HCC	35	217	249	75	327	370
	rs7574865	Chen et al.46	2015	Asian	P-B	HCC	40	211	257	343	1333	1298
	rs7574865	Clark et al.20	2013	Asian	H-B	HCC	20	102	117	28	92	86
	rs7574865	Kim et al.47	2015	Asian	P-B	HCC	20	103	160	306	1251	1293
	rs7574865	Liao et al.48	2014	Asian	P-B	HCC	25	93	104	27	113	97

P-B: population-based; H-B: hospital-based; HCC: Hepatocellular Carcinoma; W: wild allele; M: mutant allele.