Table 1.
Clinical Parameters
|
Total |
DDX3 |
HR |
95% C.I. |
P Value |
||
|---|---|---|---|---|---|---|
| Low (Alive/Dead) | High (Alive/Dead) | |||||
| Age | ||||||
| 0–18 | 49 | 24 (14/10) | 25 (14/11) | 1.09 | 0.46–2.56 | 0.85 |
| 19+ | 8 | 3 (2/1) | 5 (4/1) | 0.45 | 0.03–7.37 | 0.57 |
| Gender | ||||||
| Female | 25 | 14 (7/7) | 11 (8/3) | 0.40 | 0.10–1.56 | 0.19 |
| Male | 34 | 13 (9/4) | 21 (10/11) | 1.98 | 0.63–6.23 | 0.24 |
| Race | ||||||
| White | 30 | 15 (7/8) | 15 (9/6) | 0.77 | 0.27–2.22 | 0.63 |
| Black | 11 | 6 (4/2) | 5 (3/2) | 1.11 | 0.15–8.16 | 0.92 |
| German subgroup | ||||||
| C | 7 | 3 (0/3) | 4 (0/4) | 0.58 | 0.10–3.49 | 0.55 |
| D | 12 | 4 (3/1) | 8 (6/2) | 0.70 | 0.06–7.92 | 0.78 |
| SHH | 23 | 9 (9/0) | 14 (10/4) | NA | NA | NA |
| Subtype | ||||||
| Classic | 26 | 11 (8/3) | 15 (8/7) | 1.78 | 0.46–6.88 | 0.41 |
| Mod A | 8 | 4 (3/1) | 4 (3/1) | 1.41 | 0.09–22.64 | 0.81 |
| Nodular | 10 | 4 (4/0) | 6 (5/1) | NA | NA | NA |
| Sev A | 6 | 2 (0/2) | 4 (1/3) | 0.16 | 0.01–1.75 | 0.13 |
Correlations between DDX3 and other clinicopathological variables in pediatric medulloblastoma patients. P values calculated by Cox proportional hazard analysis. HR, Hazard Ratio; C.I., Confidence Interval.