TABLE 7.
Clinical characteristics of the 12 cases of GCT recurrence
| Case No. | Age | Race | Surgery | Chemotherapy | Stage | LN Status | DOR (mo) | Vital Status | Recurrence Site |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 25 | CA | USO (Lt), staging | BEP | II | 0/5 | 24 | Alive | Ascitis, rt ovarian pelvic-abdominal mass. Large necrotic left inguinal LN or possibly a direct hernia |
| 2 | 68 | CA | TAHBSO, omentectomy | Depolupron | IIA | 90 | Alive | Pelvic side wall, ischeorectal fossa | |
| 3 | 60 | CA | USO, staging | BEP | IIIA | 0/10, 0/1 | 31 | Alive | Pelvis, diaphragm/liver |
| 4 | 58 | CA | TAHBSO | None | IIB | 0/15, 0/5 | 85 | Dead | Pelvic, pararectal |
| 5 | 50 | O | BSO | BEP | IC | 0/2, 0/8 | 38 | Alive | Pelvic, lung, liver |
| 6 | 63 | AA | TAHBSO | None | IA | 30 | Dead | Abdomen, pelvis, peritoneum | |
| 7 | 22 | AA | USO | BEP | IIIC | 26 | Dead | Ovarian | |
| 8 | 36 | AA | TAHBSO | BEP, 2nd cytored, cytox/Avast | IIIA | 0 | 49 | Alive | Pelvis, omentum |
| 9 | 63 | CA | TAHBSO | Vinbl/BP | NA | 60 | Dead | Ascitis, intermediate iliac LN, pelvis, abdominal, lung, liver | |
| 10 | 57 | CA | TAHBSO | Carbo/taxol | IIIC | 64 | Alive | Diaphr, peritoneum, pelvis, abdominal wall, omentum | |
| 11 | 51 | CA | TAHBSO | CT-BEP-Cytox/Av-2nd cytored-Gem-Doxil-phase I | IC | 42 | Alive | Liver, bowel | |
| 12 | 80 | CA | TAHBSO | Yes (NA) | IIIC | 240 | Dead | Pelvis, peritoneum, omentum |
Bold values are statistically significant.
Avast. indicates avastin; BEP, bleomycin, etoposide, platinum; BP, bleomycin, platinum; Carbo, carboplatin; CT, carboplatin, taxol; Cytored, cytoreduction; cytox, cytoxan; DOR, date of recurrence; Gem, gemcitabine; NA, not available; O, other; TAHBSO, total abdominal hysterectomy with bilateral salpingo-oophorectomy; Vinbl, vinblastine.