Table 1.
Histopathologic spectrum of childhood enteropathies
| Normal villus morphology | Villus atrophy/inflammation | Specific or characteristic features |
|---|---|---|
| Congenital chloride diarrhoea | Autoimmune enteropathy and IPEX | Lipid-filled enterocytes • ABL • HBL • CRD |
| Carbohydrate malabsorption | Microvillus inclusion disease | Absence of plasma cells • Immunodeficiency |
| Sucrose isomaltase deficiency | Tufting enteropathy | Lymphangiectasia • Primary intestinal lymphangiectasia |
| Gluten sensitive enteropathy | Histiocytic infiltration in the lamina propria • Metabolic storage disorders |
|
| Eosinophilic gastroenteritis | Infectious agents |