Table 2.
Baseline demographics of lung cancer patients with and without idiopathic pulmonary fibrosis (IPF) from institution, and lung cancer in overall population of state of Pennsylvania
| Variables | Lung cancer with IPF | Lung cancer without IPF (institutional data) | Lung cancer without IPF (population data) | p-values column 1 vs. 3 | |||
|---|---|---|---|---|---|---|---|
| N | Results | N | Results | N | Results | ||
| Age in years, median (IQR) | 31 | 65 (62–71) | 4176 | 67 (60–75) | 104,954 | 69 (61–77) | 0.03 |
| Gender (% male) | 31 | 19 (61%) | 4176 | 2023 (48%) | 104,954 | 53,800 (51%) | 0.16 |
| Ethnicity (% Caucasian) | 31 | 30 (97%) | 4176 | 3679 (88%) | 104,954 | 89,643 (85%) | 0.07 |
| Smoking – never | 31 | 7 (23%) | 4176 | 395 (10%) | NA | < 0.001 (column 1 vs 2) | |
| former | 24 (77%) | 2362 (57%) | |||||
| current | 0 | 1361 (33%) | |||||
| Mortality over observation period (%) | 31 | 26 (84%) | 4176 | 2644 (63%) | 104,954 | 78,254 (75%) | 0.2 |
| Survival time in months, median (IQR) | 26 | 5 (1–10) | 4176 | 13 (6–26) | NA | NA | 0.002 (column 1 vs 2) |
Definition of abbreviations: IQR Interquartile range. Column 1 = Lung cancer with IPF; column 2 = Lung cancer with non-IPF ILD; column 3 = Lung cancer in general population in Pennsylvania. NA not available. Survival time was calculated by the time from lung cancer diagnosis to the date of expiration, or the time of registry data review