Table 1.
Multinomial logistic regression: Influence of the clinical, biochemical and neuroimaging variables on the outcome variables (morbidity and mortality) at 3 months from stroke onset
| Ischemic stroke | Intracerebral hemorrhage | |||||||
|---|---|---|---|---|---|---|---|---|
| Morbidity | Mortality | Morbidity | Mortality | |||||
| OR (95% CI)* | p | OR (95% CI)* | p | OR (95% CI)* | p | OR (95% CI)* | p | |
| WHOLE SAMPLE | ||||||||
| Age (year) | 1.03 (1.02–1.04) | < 0.001 | 1.06 (1.05–1.07) | < 0.001 | 1.01 (0.99–1.03) | 0.148 | 1.04 (1.02–1.06) | 0.001 |
| Stroke on awakening | 1.35 (1.06–1.72) | 0.014 | 1.57 (1.06–2.37) | 0.024 | ||||
| Maximum axillary temperature - first 24 h (°C) | 1.51 (1.33–1.71) | < 0.001 | 2.22 (1.06–2.37) | < 0.001 | 1.32 (0.97–1.79) | 0.076 | 1.92 (1.37–2.68) | < 0.001 |
| Baseline glycemia (mg/dL) | 1.00 (1.00–1.00) | < 0.001 | 1.00 (1.00–1.00) | < 0.001 | ||||
| Fibrinogen (mg/dL) | 1.00 (1.00–1.00) | 0.019 | 1.00 (1.00–1.00) | 0.065 | ||||
| White blood cells (×103/mL) | 1.11 (1.09–1.14) | < 0.001 | 1.23 (1.19–1.28) | < 0.001 | ||||
| Baseline volume of hematoma (mL) | 1.03 (1.02–1.04) | < 0.001 | 1.05 (1.04–1.06) | < 0.001 | ||||
| PERIOD 2008–2011 | ||||||||
| Age (years) | 1.02 (0.99–1.05) | 0.079 | 1.05 (1.02–1.09) | 0.001 | ||||
| Maximum axillary temperature - first 24 h (°C) | 1.20 (0.86–1.64) | 0.280 | 2.37 (1.47–3.82) | < 0.001 | ||||
| Baseline glycemia (mg/dL) | 1.00 (1.00–1.00) | 0.001 | 1.00 (1.00–1.01) | 0.047 | ||||
| Fibrinogen (mg/dL) | 1.00 (1.00–1.00) | 0.043 | 1.00 (1.00–1.00) | 0.123 | ||||
| C-reactive protein (mg/L) | 1.11 (1.05–1.17) | < 0.001 | 1.22 (1.14–1.31) | < 0.001 | ||||
| TOAST: | ||||||||
| - Lacunar | 0.29 (0.13–0.64) | 0.002 | 1.14 (0.13–9.90) | 0.905 | ||||
| - Cardioembolic + Indeterminate | 1.32 (0.90–1.93) | 0.153 | 3.08 (1.48–6.40) | 0.003 | ||||
| - Atherothrombotic + Others | ref. | ref. | ||||||
| Ischemic injury volume in 2nd CT (mL) | 1.04 (1.03–1.05) | < 0.001 | 1.05 (1.04–1.06) | < 0.001 | ||||
| Baseline hematoma volume (mL) | 1.03 (1.01–1.05) | 0.001 | 1.08 (1.05–1.10) | < 0.001 | ||||
| PERIOD 2012–2017 | ||||||||
| Age (years) | 1.04 (1.03–1.05) | < 0.001 | 1.07 (1.05–1.09) | < 0.001 | 1.01 (0.97–1.04) | 0.679 | 1.05 (1.01–1.10) | 0.025 |
| Maximum axillary temperature - first 24 h (°C) | 1.12 (1.08–1.15) | < 0.001 | 1.24 (1.17–1.30) | < 0.001 | ||||
| Baseline glycemia (mg/dL) | 1.00 (1.00–1.00) | 0.019 | 1.00 (1.00–1.00) | < 0.001 | ||||
| Fibrinogen (mg/dL) | 1.00 (1.00–1.01) | 0.015 | 1.00 (0.99–1.00) | 0.177 | ||||
| White blood cells (×103/mL) | 1.12 (1.08–1.15) | < 0.001 | 1.24 (1.17–1.30) | < 0.001 | ||||
| Baseline hematoma volume (mL) | 1.03 (1.01–1.06) | 0.001 | 1.05 (1.03–1.07) | < 0.001 | ||||
| Edema volume in 2nd CT (mL) | 1.02 (0.98–1.05) | 0.290 | 1.04 (1.00–1.07) | 0.047 | ||||
*Adjusted OR. Good outcome was considered the reference category to calculate the ORs (CI 95%)