. 2018 Oct 3;18:147. doi: 10.1186/s12876-018-0871-2

Table 1.

Anthropometric and biochemical parameters of the study subjects

	Control (n = 12)	Steatosis (n = 20)	Non-defining NASH (n = 38)	NASH (n = 18)	P
Age (years)	33.4 ± 12.9	39.1 ± 12.1	34.2 ± 10.4	34.2 ± 13.1	NS
BMI (kg/m²)	38.1 ± 8.5	37.7 ± 5.02	40.4 ± 7.3	39.4 ± 5.9	NS
Glucose (mmol/L)	4.9 (4.6–5.3)	5.5 (4.8–7.3)	5.5 (5.2–6.5)	6.6 (5.7–8.8)	< 0.05^#, ^∆, ^&, ^╪
Insulin (μIU/mL)	15.3 (12.9–23.1)	19.6 (12.9–31.4)	26.5 (19.6–41.5)	33.4 (20.0–50.8)	< 0.05^#, ^∆, ^§, ^&
HOMA-IR	3.6 (3.1–4.4)	4.9 (3.9–8.2)	7.3 (5.2–10.6)	11.5 (5.8–16.9)	< 0.05*, ^#, ^∆, ^§, ^&
C reactive protein (mg/L)	4.95 (2.75–6.85)	5.9 (4.1–7.4)	6.7 (5.5–11.3)	6.8 (5.1–10.3)	NS
Triglycerides (mmol/L)	1.59 (0.96–2.45)	1.43 (1.18–2.04)	1.90 (1.23–2.34)	1.95 (1.52–6.29)	NS
Total Cholesterol (mmol/L)	4.7 ± 0.9	4.8 ± 0.9	4.8 ± 0.6	5.4 ± 1.0	NS
HDL-C (mmol/L)	1.05 (0.96–1.50)	1.12 (0.99–1.27)	1.01 (0.83–1.10)	0.92 (0.75–1.02)	NS
LDL-C (mmol/L)	3.09 (1.83–3.36)	2.94 (2.15–3.12)	2.71 (2.16–3.35)	2.53 (2.29–3.51)	NS
ALT (IU/mL)	19.4 (14.0–28.6)	25.2 (21.0–37.5)	35.8 (27.3–60.2)	76.5 (50.3–128.8)	< 0.05^#, ^∆, ^&, ^╪
AST (IU/mL)	19.5 (15.0–25.4)	20.2 (14.7–25.9)	24.1 (18.5–35.2)	50.5 (29.2–90.7)	< 0.05^∆, ^§, ^&, ^╪
GGT (IU/mL)	35.4 (21.6–53.3)	39.5 (20.2–66.5)	43.5 (26.5–64.0)	55.8 (37.5–90.5)	NS

Note: BMI body mass index, HOMA-IR homeostasis model assessment for insulin resistance, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine transaminase, AST aspartate transaminase, and GGT gamma glutamyltranspeptidase. ^*, P < 0.05 between the control and steatosis groups; ^#, P < 0.05 between the control and non-defining NASH groups; ^∆, P < 0.05 between the control and NASH groups; ^§, P < 0.05 between the steatosis and non-defining NASH groups; ^&, P < 0.05 between the steatosis and NASH groups; ^╪, P < 0.05 between the non-defining NASH and NASH groups; and NS, none significance