Table 4.
Response to Induction Therapy According to Mir-128 and Let-7b Expression Levels in Pediatric ALL Patients
| miRNA-128 | P-value | Let-7b | P-value | |||
|---|---|---|---|---|---|---|
| Over expression | Under expression | Over expression | Under expression | |||
| (n=45) | (n=8) | (n=31) | (n=35) | |||
| Hematological response | 0.185 | 0.185 | ||||
| Complete remission | 41 (91.1)** | 6 (75)** | 27 (87.1)** | 30 (85.7)** | ||
| Not in complete remission | 4 (8.9)** | 2 (25)** | 4 (12.9)** | 5 (14.3)** | ||
| Minimal Residual Disease (MRD) | 0.453 | 0.135 | ||||
| Complete remission | 25 (55.6)** | 3 (37.5)** | 19 (61.3)** | 15 (42.9)** | ||
| Not in complete remission | 20 (44.4)** | 5 (62.5)** | 12 (38.7)** | 20 (57.1)** | ||
**
Number (%)