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. 2018 Aug 30;22(5):334–340. doi: 10.1080/19768354.2018.1512521

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Differential induction of ACSL-4 by bromelain between Kras wild-type CRCs and Kras mutant CRCs. (a) CacO₂ and DLD-1 CRCs were treated with 50 μg/mL of bromelain and analyzed for the expression levels of genes. The results are presented as fold-change of the expression levels of miRNAs in DLD-1 cells. (b) Interactome between genes and miRNAs whose expression levels were changed in CacO₂ cells compared to in DLD-1 cells was presented by IPA.