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Effect of CLDN6 knockdown on activation of PI3K pathway in HEC-1B cells.
Notes: (A) The expressions of PI3K, AKT, and mTOR in EC cells 72 h after transfection examined using western blotting analysis. (B) Bars present means ± SD. The content of protein was normalized with the expression of GAPDH. **P<0.001 compared with the respective non-transfected group.
Abbreviations: CLDN6, claudin-6; EC, endometrial carcinoma.
