Fig. 3.

A Retinal progenitor cells for transplantation. B–D These cells demonstrated early neural retinal progenitor marker (CHX10) and eye field marker (PAX6), but photoreceptor marker (OPN1SW) was not present. E Quantitative RT-PCR results of retinal progenitor cells (RPCs) for transplantation. The results are shown as binary logarithm (log2) as the expression levels of the RPCs and spherical neural masses (SNMs) compared to the undifferentiated human iPSCs. A value of zero represents no change in gene expression between two types of cells. Red bar comparison between iPSCs and SNMs, blue bar comparison between iPSCs and RPCS. Scale bars 50 μm. CHX10 Ceh-10 homeodomain containing homolog, PAX6 paired box 6, OPN1SW opsin 1 short-wave-sensitive, RT-PCR reverse transcription polymerase chain reaction. iPSC induced pluripotent stem cell