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Real-time quantitative PCR analysis of TNF-α, IL-1α and MMP-2 gene expression in the 2 and 4 weeks groups. A TNF-α, B IL-1α, and C MMP-2 gene expression in the 2 week groups. D TNF-α, E IL-1α, and F MMP-2 gene expression in the 4 weeks groups (*p < 0.01, **p < 0.001)
