Fig. 1.

A T2-MRI images of a representative group-1 patient: (left) the situation before micro-sequestrectomy of L4/5; (middle) slight increase in volume and water content by ADCT injection in L4/5; (right) recrudescence disc herniation of L4/5. B T2-MRI images of a group-1 patient with additional Modic changes: (left) the situation before micro-sequestrectomy of L5/S1 Modic Type I; (middle) slight increase in volume and water content by ADCT injection in L5/S1 Modic Type I; (right) recrudescence disc herniation of L5/S1 Modic Type I and increased zone of edema; C Representative T2-MRI images of an group-2 patient: (left) the situation before micro-sequestrectomy of L5/S1; (right) recrudescence without ADCT treatment. D T2-MRI image of a representative group-3 patient, the situation before micro-sequestrectomy L5/S1