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Effects of remifentanil treatment on bone resorption. The resorption pits were visualized and quantified by a laser scanning of cell-removed dentin discs. A Bone resorption assay showed that remifentanil decreased resorption pits on dentin discs. B Effect of remifentanil on bone resorbed area (*p < 0.05; **p < 0.01; ***p < 0.001). CON control, M-CSF macrophage-colony stimulating factor, RANKL receptor activator of nuclear factor kappa B ligand
