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. 2018 Sep 14;15(5):575–590. doi: 10.1007/s13770-018-0159-1

Table 2.

Imaging modalities of injectable hydrogel and their tissue engineering applications

Imaging modalities Source Typical penetration depth Contrast agents and molecular probes Spectral resolution Gelation method Tissue engineering applications References
Computer tomography x-ray >10 cm Iodine, barium 12–50 μm Thermal Prevention of fragile fracture, bone regeneration [49, 5153]
PET/Micro-PET γ-rays >10 cm Fluorodeoxyglucose (FDG) 18F. 11C, 15O 1–2 mm Cross-linking Tissue regeneration [43, 47, 50, 56]
Ultrasound Acoustic reflection 0.1–10 cm Microbubbles, nanoparticles 50 μm Self-assembling, thermal Bone regeneration [44, 46, 57, 58]
Magnetic resonance imaging Radio wave >10 cm Gadolinium, dysprosium, iron oxide particles 4–100 μm Charge-based cross-linking Regenerative medicine, drug delivery [45, 48, 6068]
Optical imaging light Several mm >0.3 μm Charge-based cross-linking Regenerative medicine, drug delivery [66, 69, 73]