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. 2018 Aug 10;7:1233. [Version 1] doi: 10.12688/f1000research.15579.1

Figure 1. RNA:DNA-hybrids accumulate in photoreceptor nuclei.

Figure 1.

( a) Labelled diagram shows stratified organization of retinal layers and cell types. ( b) Immunofluorescence with DNA:RNA hybrid specific S9.6 antibody of mice retinal cells. Tissue was proteolysed and disintegrated for staining (see Methods). Photoreceptors (outer nuclear layer cells) can be identified by typical inverted chromatin, as seen by DAPI stain.