Table 2.
Clinical variables of the 98 coronary artery disease patients with or without cardiovascular event
| Variables | Participants without cardiovascular events (n = 55) | Participants with cardiovascular events (n = 43) | P-value |
|---|---|---|---|
| Age (years) | 66.00 ± 8.60 | 65.21 ± 8.94 | 0.658 |
| Height (cm) | 162.13 ± 7.67 | 161.47 ± 7.45 | 0.668 |
| Body weight (kg) | 67.40 ± 11.16 | 68.25 ± 11.02 | 0.709 |
| Body mass index (kg/m2) | 25.56 ± 3.27 | 26.07 ± 2.91 | 0.425 |
| SBP (mmHg) | 128.40 ± 15.49 | 136.37 ± 20.28 | 0.030a |
| DBP (mmHg) | 70.98 ± 10.13 | 73.16 ± 8.49 | 0.260 |
| Total cholesterol (mg/dL) | 158.71 ± 27.81 | 172.93 ± 37.53 | 0.034a |
| Triglycerides (mg/dL) | 108.00 (89.00–151.00) | 129.00 (91.00–195.00) | 0.184 |
| HDL-C (mg/dL) | 44.27 ± 11.19 | 45.88 ± 14.01 | 0.528 |
| LDL-C (mg/dL) | 93.05 ± 23.94 | 100.58 ± 27.92 | 0.154 |
| Fasting glucose (mg/dL) | 106.00 (95.00–132.00) | 108.00 (95.00–157.00) | 0.564 |
| Blood urea nitrogen (mg/dL) | 16.75 ± 5.68 | 16.65 ± 5.47 | 0.934 |
| Creatinine (mg/dL) | 1.10 (0.90–1.30) | 1.00 (0.90–1.40) | 0.746 |
| Glomerular filtration rate (mL/min) | 68.29 ± 17.44 | 69.61 ± 21.20 | 0.736 |
| Leptin (ng/mL) | 4.59 (2.79–8.51) | 9.91 (4.32–34.49) | 0.001a |
| C-reactive protein (mg/dL) | 0.18 (0.14–0.24) | 0.21 (0.17–0.37) | 0.018a |
| Female (%) | 11 (20.0) | 10 (23.3) | 0.697 |
| Diabetes (%) | 24 (43.6) | 23 (53.5) | 0.333 |
| Hypertension (%) | 39 (70.9) | 37 (88.6) | 0.075 |
| ACE inhibitor use | 19 (34.5) | 10 (23.3) | 0.224 |
| ARB use | 17 (30.9) | 20 (46.5) | 0.114 |
| β-blocker use | 32 (58.2) | 26 (60.5) | 0.819 |
| CCB use | 15 (27.3) | 18 (41.9) | 0.129 |
| Statin use | 42 (76.4) | 29 (67.4) | 0.327 |
| Fibrate use | 6 (9.1) | 9 (20.9) | 0.096 |
Notes: Values for continuous variables given as mean ± SD and compared by Student’s t-test; variables not normally distributed given as medians and interquartile range and compared by Mann–Whitney U test; values are presented as number (%), and analysis was performed using the chi-squared test.
a
P < 0.05 was considered statistically significant.
Abbreviations: ACE, angiotensin-converting enzyme; ARB, angiotensin-receptor blocker; CCB, calcium-channel blocker; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure.