Table 1.

Proposed Areas for Future Research Based on the Framework for Deciding When to Say No to Your Listed Patient

Quantifying Transplant Benefit (moving vertically in Fig. 1)	Improving Transplant Benefit by Shifting Candidates From C → B or From B → A (moving horizontally in Fig. 1)
Pretransplant measures of frailty	Prehabilitation
Sarcopenia	Transplanting patients with greater transplant nonresponsive factors with higher donor quality
Biomarkers of frailty, sarcopenia, or renal dysfunction	“Early” transplant (i.e., at a lower MELD score) with living donor liver transplantation