Table 3. Pathogenic markers theorized in NPSLE.
TWEAK - tumor necrosis factor-like weak inducer of apoptosis, NPSLE - neuropsychiatric systemic lupus erythematosus.
Markers |
NMDAR antibody (NR1/NR2) |
Anti-cardolipin, Beta 2 glycoprotein |
Anti-ribosomal P |
Anti-endothelial receptor |
Sm/Ro (SSA)/U1 RNP |
Interferons such as IL-2, IL-6, IL-8, IL-10, TNF, IFN-α, IFN-γ |
Chemokine like CXCL 10 and CCL 5 |
Septins |
Anti-histone |
Inflammatory markers |
B cells |
Atherosclerosis |
Immune complex deposits |
TWEAK |