Fig 3. Cloud plots representing the m/z features which display statistically significant differences in peak intensities between the extraction conditions.

Panel A: Comparison of features obtained with method 2A vs. method 1 in each of the three cyanobacterial strains. Panel B: Comparison of features obtained with method 2B vs method 2A. For brevity, only those features are displayed in cloud plots that show a fold change ≥ 1.5 and a p-value of ≤ 0.01. The intensity of the color represents the p-value (darker color for lower p-value) while the size of the bubble corresponds to the fold change (larger bubble for greater fold change). This figure was obtained using the cloud plot feature [46] from the XCMS online software using our data.