Table 4. Logistic regression analysis of the four variables as predictive factors for IFX therapeutic response.
| Independent variable | β | SE β | Wald χ2 | p value | ORa | 95%CI OR |
|---|---|---|---|---|---|---|
| Disease duration | -0.1050 | 0.0315 | 11.13 | 0.0009 | 0.035 | 0.005–0.252 |
| Double dosing | -1.1413 | 0.2764 | 17.05 | <0.0001 | 0.102 | 0.035–0.301 |
| Combination treatment with IM | 0.7265 | 0.2595 | 7.84 | 0.0051 | 4.276 | 1.546–11.826 |
| TNF-α- 857C>T (C/C)b (rs1799724) | -0.4160 | 0.2491 | 2.79 | 0.0949 | 0.435 | 0.164–1.155 |
| Constant | 1.3322 | 0.4976 | 7.17 | 0.0074 |
aOdds ratio (OR) is given with 95%CI after using a logistic regression analysis of the four variables as predictive factors for IFX therapeutic response.
bThe homozygous genotype with minor allele was combined to heterozygous genotype within parenthesis is indicates reference group.
Logit(R) = 1.3322 − 0.1050×Disease duration − 1.1413×Double dosing + 0.7265×Combination treatment with IM − 0.4160×TNF-α- 857C>T
R: Remission in IFX therapeutic response