Table 2.
Specialized exosome membrane composition resembling lipid raft
| Exosome membrane | Reference | Exosome source | Characteristics |
|---|---|---|---|
| Exposure of PS on outer leaflet | 46 | Human amniotic fluid | Diversity of negative charge |
| 47 | Murine B16BL6 culture sup. | Engulfment by macrophages by scavenger receptors | |
|
Sphingolipids Cholesterol |
49 | PC‐3 culture sup. | Sphingomyelin concentration compared with parent cells |
| 50 | LIM1215 culture sup. | Identification of many sphingolipids by lipidome analysis | |
| GPI‐anchored proteins | 54 | NKG2D ligands as GPI‐anchored proteins for immune activation | |
| GPCR | 56 | Human cell culture sup. Human saliva | Detection of several exosomal GPCR |
GPCR, G protein‐coupled receptor; GPI, glycosylphosphatidylinositol; NKG2D, natural‐killer group 2, member D; PC‐3, prostate cancer‐3; PS, phosphatidylserine; sup., supernatant.