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Combined treatment with LBH589 and simvastatin (Sim) significantly prolonged the survival of MDA‐MB‐231 tumor‐bearing mice
| Group | Median survival time (MST, days) |
|---|---|
| Vehicle | 43.5 |
| LBH589 (0.5 mg/kg) | 56.0 |
| Sim (10 mg/kg) | 62.0* |
| Combination | 90.0*, *** |
* P < .05 compared with vehicle.
** P < .05 compared with vehicle.
*** P < .05 compared with Sim 10 mg/kg.
