Figure 6.

Expression of n339260 promoted vascular mimicry (VM) formation, cancer‐related microRNAs (miRNAs) expression in vitro. A, HepG2 n339260 expressed higher levels of n339260 than control cells as analyzed by qRT‐PCR; knockdown of n339260 expression in HepG2‐c‐Myc‐SOX2 (HCS) cells. B‐C, Expression of c‐myc, sox2, Nanog, CD133 and vascular endothelial (VE)‐cadherin (B) in HepG2 n339260, and tubular channel formation on Matrigel and in Matrigel in these cells (C). Effect of n339260 knockdown on c‐myc, sox2, Nanog, CD133 and VE‐cadherin expression (B) and VM formation (C). D‐E, Cancer‐related miRNAs expression following n339260 ectopic expression in HepG2 (D) and n339260 knockdown in HCS (E) by qPCR