Figure 3.

Re-entrainment of Adar2-KO mouse activities to a new LD cycle. (a,b) Representative double-plotted actograms of wheel-running activities in the jet lag paradigm. The area with gray shading indicates the dark period. (c) Activity onset in the jet lag paradigm with an 8-h advance and an 8-h delay (mean ± s.e.m.; *P < 0.05 by Student’s t-test). (d) Days required for re-entrainment to the new LD cycles after an abrupt shift of the 12-h/12-h LD cycles with an 8-h advance and an 8-h delay (mean ± s.e.m.; n.s. P ≥ 0.05, *P < 0.05 by Student’s t-test). The numbers of animals are indicated in parentheses.