Table 1.
Comparison of baseline demographic, clinical and laboratory characteristics between survivors and non-survivors
| Variable | Total (n = 209) | Survivors (n = 163) | Non-survivors (n = 46) | p value |
|---|---|---|---|---|
| Age (year) | 40.2 ± 14.1 | 39.5 ± 13.6 | 42.8 ± 15.8 | 0.20 |
| Male | 124 (59) | 99 (61) | 25 (54) | 0.4 |
| Etiology | 0.5 | |||
| Biliary | 107 (51) | 79 (49) | 28 (61) | |
| Alcohol | 50 (24) | 39 (24) | 11 (24) | |
| Idiopathic | 33 (16) | 26 (16) | 7 (15) | |
| Others | 19 (9) | 19 (11) | 0 | |
| Referred patient | 144 (69) | 101 (62) | 43 (94) | 0.001 |
| Delay in presentation (days) | 8 (0–90) | 6 (0–90) | 17 (2–90) | 0.001 |
| Intervention prior to referral (number of patients) | 10 (7) | 6 (6) | 4 (9) | 0.4 |
| CCI > 2 | 24 (11) | 11 (7) | 13 (28) | 0.001 |
| Prophylactic antibiotic use | 65 (31) | 43 (26) | 22 (48) | 0.001 |
| APACHE II at admission | 6 (0–28) | 6 (0–19) | 11 (3–28) | 0.001 |
| Marshall score at admission | 0 (0–7) | 0 (0–5) | 3 (0–7) | 0.001 |
| Modified CTSI | 8 (0–10) | 8 (0–10) | 10 (4–10) | 0.001 |
| Necrosis | 112 (54) | 75 (46) | 37 (80.5) | 0.001 |
| Persistent OF | 81 (39) | 39 (24) | 42 (91) | 0.001 |
| Early OF | 58 (28) | 33 (20) | 25 (54.3) | 0.001 |
| IPN | 108 (52) | 69 (42) | 39 (85) | 0.001 |
| MDR organism | 80 (38) | 41 (25) | 39 (85) | 0.001 |
| XDR organism | 52 (25) | 25 (15) | 27 (59) | 0.001 |
| Fungal infection | 27 (13) | 14 (9) | 13 (28) | 0.001 |
| Extra-pancreatic infection | 29 (14) | 17 (11) | 12 (26) | 0.01 |
| Air in collection prior to interventiona | 32 (24) | 27 (30) | 5 (12) | 0.03 |
| Need for any intervention | 93 (45) | 54 (33) | 39 (85) | 0.001 |
| Surgical intervention | 28 (13) | 12 (7) | 16 (35) | 0.001 |
| Walled off necrosisa | 54 (41) | 40 (44) | 14 (34) | 0.3 |
| Duration of hospital stay (day) | 14 (3–120) | 12 (3–120) | 27 (5–100) | 0.001 |
Values as mean ± SD, median (range), and n (%) as appropriate
CCI Charlson co morbidity index, MDR multidrug resistant, OF organ failure, IPN infected pancreatic necrosis, CTSI CT severity index
aCollection present in 133 patients