Table 1.
Demographics and pre treatment characteristics of all participants treated
| Moxidectin | Ivermectin | ||
|---|---|---|---|
| Total participants | 978 | 494 | |
| Participants in Nord Kivu, DR Congo | 305 | 155 | |
| Participants in Nord Ituri, DR Congo | 315 | 157 | |
| Participants in Lofa, Liberia | 200 | 99 | |
| Participants in Nkwanta, Ghana | 158 | 83 | |
| African origin | 978 (100%) | 494 (100%) | |
| Age (years) | 41·5 (16·4) | 42·8 (16·1) | |
| Adolescents (12–17 years old) | 55 (6%) | 24 (5%) | |
| Weight (kg) | 51·6 (8·40) | 51·6 (7·90) | |
| Height (cm) | 158·9 (8·74) | 159·4 (8·53) | |
| Sex* | |||
| Males | 626 (64%) | 315 (64%) | |
| Females | 352 (36%) | 179 (36%) | |
| Participants with <20 microfilariae per mg of skin* | 281 (29%) | 150 (30%) | |
| Skin microfilariae density across all participants | 38·8 (30·5) | 41·2 (31·3) | |
| Skin microfilariae density among ≥18 year-olds | 39·4 (31·0) | 41·9 (31·7) | |
| Skin microfilariae density among 12–17-year-olds | 29·2 (17·7) | 27·0 (15·3) | |
| Participants with >10 microfilariae in the anterior chamber across both eyes | 136 (14%) | 76 (15%) | |
| Microfilariae in the anterior chamber across both eyes in participants with >10 microfilariae in the anterior chamber across both eyes | 26·1 (19·6) | 26·1 (18·2) | |
Data are arithmetic mean (SD) or n (%).
*
Stratification variable.