Table 1.
ICD- (n = 69) | ICD+ (n = 31) | p-value | |
---|---|---|---|
Age, years | 68.79 ± 7.82 | 63.55 ± 9.77 | 0.01 |
Gender, male (%) | 37 (53.6) | 17 (54.8) | 0.91 |
Age at PD onset, years | 62.5 ± 7.75 | 57.5 ± 9.52 | 0.02 |
Evolution, months | 65.6 ± 3.76 | 77.8 ± 3.87 | 0.25 |
UPDRS III | 23.4 ± 9.88 | 19.9 ± 9.65 | 0.11 |
H&Y* | 2(2-2.5) | 2(2-2) | 0.06 |
LEDD, mg | 533.1 ± 451.6 | 702.2 ± 416.9 | 0.07 |
Proportion of agonist use (%) | 41 (59) | 26 (84) | 0.02 |
QUIPs | 0.06 | 1.84 | < 0.001 |
MIDI | 0.29 | 3.3 | < 0.001 |
BIS-11 | 56.35 ± 7.0 | 58.33 ± 7.72 | 0.23 |
Motor | 19.31 ± 2.52 | 19.37 ± 2.95 | 0.93 |
Nonplanning | 20.79 ± 4.07 | 22.23 ± 4.7 | 0.15 |
Attentional | 16.25 ± 1.98 | 16.73 ± 1.98 | 0.27 |
PCPT commission errors ratio | 0.378 ± 0.2 | 0.376 ± 0.2 | 0.96 |
PCPT correct RT, ms | 480 ± 75 | 465 ± 57 | 0.24 |
PCPT error RT, ms | 447 ± 163 | 426 ± 131 | 0.49 |
PCPT correct targets ratio | 0.94 | 0.95 | 0.59 |
Current smokers (%) | 3 (4.3) | 6 (19) | 0.02** |
Lifetime smokers (%) | 32 (46) | 20 (65) | 0.93 |
Age at smoking onset | 19.65 ± 4.48 | 15.53 ± 3.11 | < 0.001 |
Current alcohol users (%) | 41 (59) | 27 (87) | 0.006 |
Lifetime alcohol users (%) | 52 (75) | 30 (97) | 0.009 |
Lifetime illegal drugs users (%) | 3 (5) | 4 (14) | 0.20** |
Mean ± standard deviation and proportions are shown unless otherwise specified. t-test is used for central measures and Chi-square for proportions unless other test specified.
Median (interquartile range), Wilcoxon–Mann–Whitney test significance is shown.
Fisher exact test significance is shown.
ICD, impulse control disorder; PD, Parkinson's disease; UPDRS, Unified Parkinson's Disease Rating Scale; H&Y Hoehn and Yahr scale; LEDD, levodopa equivalent daily dose; QUIPs, Short version of Questionnaire for Impulsive-Compulsive Disorders, MIDI, Minnesota Impulsive Disorders Interview; BIS-11, Barrat Impulsiveness Scale; PCPT, PEBL Continuous Performance Task; RT, reaction time; ms, milliseconds.