Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 28;9:1110. doi: 10.3389/fphar.2018.01110

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Li, Cui, Cai, Lin, Song, Zhou, Xiong, Zhou, Bian and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

TXYF treatment affected the level of 5-HT and the expression of associated pathway genes in IBS-D rats. (A) TXYF treatment decreased the colonic 5-HT level in IBS-D model rats. (B) TXYF treatment up-regulated the expression of Sert and down-regulated the expression of 5Ht2ar in colonic tissue of IBS rats (Fold change relative to the IBS group is shown). (C) After TXYF treatment, the mRNA expression levels of Tph1 and Tph2 in colonic mucosa of IBS rats were down-regulated (Fold change relative to the IBS group is shown). Control; IBS; and TXYF+IBS (n = 10 per group). Data are presented as mean ± SD. ^∗P < 0.05 and ^∗∗P < 0.01.