Table 1.
Participants' characteristics | Baclofen treatment | Clinical effects of baclofen treatment | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
References | Gender | Comorbidity | Baseline DDD | Mean daily dose | Weeks | Final DDD | Anxiety | Depression | Schizophrenia | Bulimia | Stuttering |
(30) | 1 M | Schizophrenia Anxiety | ~16 | 75 mg | 24 | 0 | ↔ | – | ↓ | – | – |
(31) | 1 M | Anxiety | ~20 | 120 mg | 36 | 0 | ↓ | – | – | – | – |
(32) | 1 M | Stuttering Depression | ~16–24 | 90 mg | >52 | 2 | - | ↓ | – | – | ↓ |
(33) | 1 M | Anxiety Depression | ~5–12 | 100 mg | 40 | 2–3 | ↔ | ↔ | – | – | – |
(34) | 3 M; 1 F | Depression Bipolar disorder | ~7–30 | 50-125 mg | 20–36 | 0 | – | – | – | – | – |
(35) | 1 F | Anxiety Bulimia | ~20 | 120 mg | 8 | 0 | – | – | – | ↔ | – |
DDD, Drinks per Drinking Day (1 drink = ~12 g of pure alcohol); F, Female; M, Male.