. 2018 Sep 5;18(5):4271–4280. doi: 10.3892/mmr.2018.9455

Table I.

Clinical data of some members in a family associated with dilated cardiomyopathy.

Patient	Age (years)	Gender	Dynamic electrocardiogram/Holter	NYHA	Cardiac symptoms at onset (age, years)	Left ventricular end-diastolic diameter (mm)	Left ventricular ejection fraction (%)	LMNA p.E82K mutation
II-1	69	Female	N			N	N	Negative
II-2	50^a	Female	N		40	N	N	–
II-3	48^a	Female	N		36	N	N	–
II-4	45^a	Male	N		35	N	N	–
II-5	57^a	Male	Pre-pacing, abnormal Q wave in leads V₁-V₄, left ventricular high voltage, slow JR with sino-capture, CRBBB, ST-T change, paired PVC, sinus arrest, paroxysmal SR; post-pacing, Frequent PVC, ST-T change, AAI	III–IV	54	69.6	45	–
II-6	54	Female	Pre-pacing, frequent PVC (bigeminal rhythm), degree I AVB, slow JR, accelerated atrioventricular rhythm, ST-T Change, poor R-wave progression in leads V₁-V₄, post-pacing, paroxysmal AF, occasional PVC, AAI	II–III	44	56.8	35	Heterozygous
II-7	52	Female	Pre-pacing, slow AF, degree III AVB, JR, ST-T change in some leads, Poor R-wave progression in leads V₁-V₄, post-pacing, AF, AAI	II–III	47	50.2	62.3	Heterozygous
III-3	41	Male	N	I		42.5	62	Negative
III-7	35	Male	N	II		49.6	55	Heterozygous
III-10	38	Male	N	I		44.3	72	Negative
III-11	34	Male	Degree I AVB	II		51.5	56	Heterozygous
III-13	30	Male	SR, ST-T change	II		51.5	56	Heterozygous
IV-6	8	Female	N			30.9	65	Negative
IV-7	4	Male	Sinus arrhythmia			28.6	73	Heterozygous

Patients succumbed to mortality due to heart failure at ages presented (DNA samples were not obtained). AAI; paroxysmal ventricular tachycardia; AF, atrial fibrillation; AVB, atrioventricular block; CRBBB, complete right bundle branch block; JR, junctional rhythm; pacing rhythm; N, normal; NYHA, New York Heart Association; PVC, premature ventricular contraction; SR, sinus rhythm. ST-T, ST segment and T wave.